Antioxidant and SPF Activity of Sunscreen Cream Preparations from 96% Ethanol Extract of Bractea Bougainvillea spectabilis Willd.

Ni Nyoman Yuliani; Siswandono .; Tristiana Erawati; Elisma .; Jefrin Sambara; Lely A. V. Kapitan; Maria I. M. Indrawati; Yorida F Maakh

doi:10.31632/ijalsr.2024.v07i04.011

Ni Nyoman Yuliani 1Doctoral Program of Pharmaceutical Sciences, Faculty of Pharmacy, Airlangga University, Indonesia 2Health Polytechnic of Ministry of Health in Kupang, Kupang, Indonesia https://orcid.org/0000-0002-7787-4297
Siswandono . Department of Pharmaceutical Sciences, Faculty of Pharmacy, Airlangga University, Indonesia
Tristiana Erawati Department of Pharmaceutical Sciences, Faculty of Pharmacy, Airlangga University, Indonesia https://orcid.org/0000-0002-5983-5614
Elisma . Health Polytechnic of Ministry of Health in Kupang, Kupang, Indonesia
Jefrin Sambara Health Polytechnic of Ministry of Health in Kupang, Kupang, Indonesia
Lely A. V. Kapitan Health Polytechnic of Ministry of Health in Kupang, Kupang, Indonesia
Maria I. M. Indrawati Health Polytechnic of Ministry of Health in Kupang, Kupang, Indonesia
Yorida F Maakh Health Polytechnic of Ministry of Health in Kupang, Kupang, Indonesia

DOI https://doi.org/10.31632/ijalsr.2024.v07i04.011

Abstract

Bractea Bougainvillea spectabilis Willd contains antioxidants which are used to brighten and moisturize the skin. Antioxidants can delay and prevent free radicals in the skin. The aim of this research is to make sunscreen cream preparations from 96% ethanol extract of Bougainvillea spectabilis Willd bractea ethanol extract with good physical quality, determine antioxidant activity and value. Sun Protection Factor (SPF) and testing the stability of sunscreen cream preparations. Testing antioxidant activity uses the DPPH Free Radical Reduction method, while determining the SPF value using in vitro using a UV-Vis spectrophotometer. The results of the research show that 96% ethanol extract of Bougainvillea spectabilis Willd bractea ethanol extract can be made into a cream that has good physical quality. Antioxidant activity of 1.5% ethanol extract (F3) bractea cream Bougainvillea spectabilis Willd with IC value₅₀amounting to 10.48 ± 3.92 (very strong category) has higher antioxidants compared to 0.5% ethanol extract cream (F1) has IC₅₀26,62 ± 6,73 (very strong category) and 1,0% ethanol extract cream (F2) has IC₅₀26.15 ± 3.22 (very strong category), compared to the positive control lower vitamin C cream 0.5% has IC₅₀6.95 ± 0.51 (very strong category). Sunscreen activity of 96% ethanol extract Bougainvillea spectabilis Willd Formula F3 has an SPF value of 21.22 ± 1.58 (ultra protection category) and has higher sunscreen activity than F1 with an SPF value of 12.48 ± 0.05 (minimal protection category) and F2 with an SPF value of 16.69 ± 0. 21 (ultra protection category) and positive control PABA2% cream SPF value 6.95 ± 0.51 (extra protection category).

Keywords: Antioxidant, Bractea Bougainvillea spectabilis Willd, Cream, SPF

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