In –vitro Antioxidant Activity of Methanolic Extract of the Roots of Bergenia ciliata

Suman Lal Shrestha; Suresh Awale; Surya Kant Kalauni

Suman Lal Shrestha Patan Multiple Campus, Patan, Lalitpur, Nepal
Suresh Awale Division of Natural Drug Discovery, Department of Translational Research, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan
Surya Kant Kalauni Central Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, Nepal

Abstract

Bergenia ciliata is an essential medicinal plant used in regions where western medicines are inaccessible due to their unavailability and high cost. The methanolic extract of Bergenia ciliataroots was separated for phytochemical elements and in-vitro antioxidant activity. The plant extract showed the rich outgrowth of secondary metabolites that play the role for biological activities. The higher antioxidant functioning of the plant is due to the occurrence of reactive elements like phenols and flavonoids. The antioxidant functioning of the plant extract was measured by DPPH free radical scavenging assay. In DPPH free radical scavenging assay the IC50 value of Bergenia ciliata was found to be 11.21μg/mL, while the IC50 value of standard ascorbic acid was found to be 45.93μg/mL

Keywords: antioxidant, DPPH, free radical scavenging, medicinal plants, methanolic extract

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