Effectiveness of Progesterone Treatment Among Pregnant Women in A Tertiary Care Teaching Hospital

Rajan Ethiraj Ugandar; J. Karthiki; Tati Reddy Navyasree; G. Swetha; D. Nagalakshmi; D. Tejavathi; D. Haseena

doi:10.31632/ijalsr.2024.v07i04.015

Rajan Ethiraj Ugandar Department of Pharmacy Practice, Santhiram College of Pharmacy, Nandyal 518501, Andhra Pradesh, India. https://orcid.org/0000-0002-7014-0864
J. Karthiki Department of Obstetrics and Gynecology, Santhiram Medical College and General Hospital, Nandyal-518502,Andhra Pradesh, India.
Tati Reddy Navyasree Department of Obstetrics and Gynecology, Santhiram Medical College and General Hospital, Nandyal-518502,Andhra Pradesh, India.
G. Swetha Department of Pharmacy Practice, Santhiram College of Pharmacy, Nandyal 518501, Andhra Pradesh, India. https://orcid.org/0009-0003-5632-8486
D. Nagalakshmi Department of Pharmacy Practice, Santhiram College of Pharmacy, Nandyal 518501, Andhra Pradesh, India. https://orcid.org/0009-0000-5739-7043
D. Tejavathi Department of Pharmacy Practice, Santhiram College of Pharmacy, Nandyal 518501, Andhra Pradesh, India https://orcid.org/0009-0009-6083-0931
D. Haseena Department of Pharmacy Practice, Santhiram College of Pharmacy, Nandyal 518501, Andhra Pradesh, India. https://orcid.org/0009-0002-1918-7349

DOI https://doi.org/10.31632/ijalsr.2024.v07i04.015

Abstract

Progesterone is essential for the maintenance of pregnancy. Threatened abortion and recurrent miscarriage are the common complications of pregnancy. This study conducted to determine the effectiveness of progesterone supplementation in preventing miscarriage in cases of threatened abortion and recurrent miscarriages, aiming to extend pregnancy beyond 24 weeks in these women. The objectives of this study are to identify the number of pregnant women treated with progesterone, to know the choice of progesterone formulation prescribed for threatened abortion and previous history of miscarriage, and to determine the effectiveness of progesterone treatment among patients with threatened abortion and previous history of miscarriage. The results showed that a total of 107 cases were treated with progesterone, Among the majority of the cases were threatened abortion cases 50 (46.42%), followed by previous history of miscarriage cases 26 (24.29%), previous history of preterm birth cases 15 (14%), primi gravida cases 12 (11.21%) and short cervix cases 4 (3.7%). The outcome of this study determines that, out of 50 (46.42%) threatened abortion cases, 46(92%) women successfully continued their pregnancies to proceed beyond 24 weeks, and 4(8%) cases got abortion. Among 26 (24.29%) previous history of miscarriage cases 25 (96.1%) women successfully continued their pregnancies and 1(3.8%) got an abortion. It also demonstrates the rate of abortion was reduced in women treated with progesterone supplementation.

Keywords: miscarriage, preterm birth, primi gravida threatened abortion, progesterone, short cervix

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References

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