Biosurfactants: Moving Towards Healthcare Applications
Abstract
Biosurfactants, fascinating molecules originating from microbial sources, have captivated researchers' imaginations for their escalating potential across a spectrum of healthcare applications. This comprehensive review explores the multifaceted world of biosurfactants, elucidating their diverse nature and exceptional physicochemical properties, propelling them toward becoming game-changers in healthcare. It represents a captivating array of compounds, boasting structural diversity encompassing glycolipids, lipopeptides, fatty acids, phospholipids, and more. These microbial marvels, formed at the intersection of hydrophilicity and hydrophobicity, offer adaptability and utility that extend across various applications. They wield the power to reduce surface and interfacial tension, making them adept at emulsifying immiscible substances. Biosurfactants serve as formidable antimicrobial agents combating drug-resistant bacteria and emerging viral threats. In the realm of wound care and tissue regeneration, biosurfactants shine. They promote wound healing and tissue repair through enhanced cell migration and regeneration opening new vistas for healthcare professionals. Biosurfactants have found their place in pharmaceutical formulations, elevating drug solubility and stability. These molecules significantly improve drug delivery systems, potentially amplifying their therapeutic efficacy. In cosmetics and personal care products, biosurfactants contribute to their emulsifying prowess, enhancing product texture and quality. They are also making their mark in the food industry, improving the solubility of bioactive compounds, and expanding the horizons of functional food additives. Biosurfactants are integral to diagnostic assays, offering improved stability and sensitivity. While biosurfactants hold immense promise, challenges include sustainability and environmental considerations. However, the burgeoning field of biosurfactants in healthcare beckons further research and development.
Keywords:
Biosurfactants, Physicochemical properties, Healthcare applications, Diagnostic assays, Pharmaceutical formulations
Downloads
Download data is not yet available.
References
Abbot, V., Paliwal, D., Sharma, A., & Sharma, P. (2022). A review on the physicochemical and biological applications of biosurfactants in biotechnology and pharmaceuticals. Heliyon, 8(8): e10149. https://doi.org/10.1016/j.heliyon.2022.e10149
Adejumo, S. A., Oli, A. N., Okoye, E. I., Nwakile, C. D., Ojiako, C. M., Okezie, U. M., Okeke, I. J., Ofomata, C. M., Attama, A. A., Okoyeh, J. N., & Esimone, C. O. (2021). Biosurfactant Production Using Mutant Strains of Pseudomonas aeruginosa and Bacillus subtilis from Agro-industrial Wastes. Advanced Pharmaceutical Bulletin, 11(3), 543–556. https://doi.org/10.34172/apb.2021.063
Adu, S. A., Naughton, P. J., Marchant, R., & Banat, I. M. (2020). Microbial biosurfactants in cosmetic and personal skincare pharmaceutical formulations. Pharmaceutics, 12(11), 1099. https://doi.org/10.3390/pharmaceutics12111099
Akbari, S., Abdurahman, N. H., Yunus, R. M., Fayaz, F., & Alara, O. R. (2018). Biosurfactants—a new frontier for social and environmental safety: a mini-review. Biotechnology Research and Innovation, 2(1),81-90. https://doi.org/10.1016/j.biori.2018.09.001
Banat, I. M., Franzetti, A., Gandolfi, I., Bestetti, G., Martinotti, M. G., Fracchia, L., Smyth, T. J., & Marchant, R. (2010). Microbial biosurfactants production, applications and future potential. Applied Microbiology and Biotechnology, 87(2), 427–444. https://doi.org/10.1007/s00253-010-2589-0
Begum, W., Saha, B., & Mandal, U. (2023). A comprehensive review on production of bio-surfactants by bio-degradation of waste carbohydrate feedstocks: an approach towards sustainable development. RSC advances, 13(36), 25599-25615. https://doi.org/10.1039/D3RA05051C
Bhadoriya, S. S., Madoriya, N., Shukla, K., & Parihar, M. S. (2013). Biosurfactants: a new pharmaceutical additive for solubility enhancement and pharmaceutical development. Biochem Pharmacol, 2(2), 113. https://doi.org/10.4172/2167-0501.1000113
Bjerk, T. R., Severino, P., Jain, S., Marques, C., Silva, A. M., Pashirova, T., & Souto, E. B. (2021). Biosurfactants: properties and applications in drug delivery, biotechnology and ecotoxicology. Bioengineering, 8(8), 115. https://doi.org/10.3390/bioengineering8080115
Campos, J. M., Stamford, T. L., Sarubbo, L. A., de Luna, J. M., Rufino, R. D., & Banat, I. M. (2013). Microbial biosurfactants as additives for food industries. Biotechnology Progress, 29(5), 1097–1108. https://doi.org/10.1002/btpr.1796
Ceresa, C., Fracchia, L., Sansotera, A. C., De Rienzo, M. A. D., & Banat, I. M. (2023). Harnessing the potential of biosurfactants for biomedical and pharmaceutical applications. Pharmaceutics, 15(8), 2156. https://doi.org/10.3390/pharmaceutics15082156
De Giani, A., Zampolli, J., & Di Gennaro, P. (2021). Recent trends on biosurfactants with antimicrobial activity produced by bacteria associated with human health: different perspectives on their properties, challenges, and potential applications. Frontiers in Microbiology, 12, 655150. https://doi.org/10.3389/fmicb.2021.655150
Dias, M. A. M., & Nitschke, M. (2023). Bacterial-derived surfactants: an update on general aspects and forthcoming applications. Brazilian Journal of Microbiology, 54(1), 103-123. https://doi.org/10.1007/s42770-023-00905-7
Dusane, D. H., Zinjarde, S. S., Venugopalan, V. P., McLean, R. J., Weber, M. M., & Rahman, P. K. (2010). Quorum sensing: implications on rhamnolipid biosurfactant production. Biotechnology & Genetic Engineering Reviews, 27, 159–184. https://doi.org/10.1080/02648725.2010.10648149
Eras-Muñoz E, Farré A, Sánchez A, Font X, Gea T. (2022) Microbial biosurfactants: a review of recent environmental applications. Bioengineered,13(5):12365-12391. https://doi.org/10.1080/21655979.2022.2074621
Flessa, S., & Huebner, C. (2021). Innovations in health care—A conceptual framework. International Journal of Environmental Research and Public Health, 18(19), 10026. https://doi.org/10.3390/ijerph181910026
Haddaji, N., Bahloul, B., Bahia, W., Bechambi, O., & Mahdhi, A. (2023). Development of nanotechnology-based drug delivery systems for controlling clinical multidrug-resistant Staphylococcus aureus and Escherichia coli Associated with Aerobic Vaginitis. Pharmaceutics, 15(8), 2133. https://doi.org/10.3390/pharmaceutics15082133
Hashim, Z. A., Maillard, J. Y., Wilson, M. J., & Waddington, R. J. (2022). Determining the potential use of biosurfactants in preventing endodontic infections. European Journal of Oral Sciences, 130(6), e12900. https://doi.org/10.1111/eos.12900
Herrmann, I. K., & Schlegel, A. A. (2022). Fostering Medical Materials Innovation. ACS Materials Au, 3(1), 24-27. https://doi.org/10.1021/acsmaterialsau.2c00054
Kaczorek, E., Pacholak, A., Zdarta, A., & Smułek, W. (2018). The impact of biosurfactants on microbial cell properties leading to hydrocarbon bioavailability increase. Colloids and Interfaces, 2(3), 35. https://doi.org/10.3390/colloids2030035
Karnwal, A., Shrivastava, S., Al-Tawaha, A. R. M. S., Kumar, G., Singh, R., Kumar, A., ... & Malik, T. (2023). Microbial Biosurfactant as an Alternate to Chemical Surfactants for Application in Cosmetics Industries in Personal and Skin Care Products: A Critical Review. BioMed Research International, 2023-2375223. https://doi.org/10.1155/2023/2375223
Khanna, A., Handa, S., Rana, S., Suttee, A., Puri, S., & Chatterjee, M. (2023). Biosurfactant from Candida: sources, classification, and emerging applications. Archives of Microbiology, 205(4), 149. https://doi.org/10.1007/s00203-023-03495-y
Kumari, K. S., Shivakrishna, P., & Ganduri, V. R. (2020). Wound healing Activities of the bioactive compounds from Micrococcus sp. OUS9 isolated from marine water. Saudi Journal of Biological Sciences, 27(9), 2398-2402. https://doi.org/10.1016/j.sjbs.2020.05.007
Ndlovu, T., Rautenbach, M., Vosloo, J. A., Khan, S., & Khan, W. (2017). Characterisation and antimicrobial activity of biosurfactant extracts produced by Bacillus amyloliquefaciens and Pseudomonas aeruginosa isolated from a wastewater treatment plant. AMB Express, 7(1), 1-19. https://doi.org/10.1186/s13568-017-0363-8
Nitschke, M., & Marangon, C. A. (2022). Microbial surfactants in nanotechnology: recent trends and applications. Critical Reviews in Biotechnology, 42(2), 294–310. https://doi.org/10.1080/07388551.2021.1933890
Ohadi, M., Forootanfar, H., Dehghannoudeh, N., Banat, I. M., & Dehghannoudeh, G. (2023). The role of surfactants and biosurfactants in the wound healing process: a review. Journal of Wound care, 32(Sup4a), xxxix–xlvi. https://doi.org/10.12968/jowc.2023.32.Sup4a.xxxix
Peele, K. A., Ch, V. R. T., & Kodali, V. P. (2016). Emulsifying activity of a biosurfactant produced by a marine bacterium. 3 Biotech, 6(2), 177. https://10.1007/s13205-016-0494-7
Perfumo, A., Rancich, I., & Banat, I. M. (2010). Possibilities and challenges for biosurfactants use in petroleum industry. Biosurfactants, 135-145.
Raza, Z. A., Shahzad, Q., Rehman, A., Taqi, M., & Ayub, A. (2022). Biosurfactants in the sustainable eradication of SARS COV-2 from the environmental surfaces. 3 Biotech, 12(10), 273. https://10.1007/s13205-022-03320-1
Ribeiro, B. G., Guerra, J. M. C., & Sarubbo, L. A. (2020). Potential food application of a biosurfactant produced by Saccharomyces cerevisiae URM 6670. Frontiers in Bioengineering and Biotechnology, 8, 434. https://doi.org/10.3389/fbioe.2020.00434
Rincón-Fontán, M., Rodríguez-López, L., Vecino, X., Cruz, J. M., & Moldes, A. B. (2020). Novel multifunctional biosurfactant obtained from corn as a stabilizing agent for antidandruff formulations based on Zn pyrithione powder. ACS omega, 5(11), 5704-5712. https://doi.org/10.1021/acsomega.9b03679
Ron, E. Z., & Rosenberg, E. (2001). Natural roles of biosurfactants. Environmental Microbiology, 3(4), 229–236. https://doi.org/10.1046/j.1462-2920.2001.00190.x
Santos, D. K., Rufino, R. D., Luna, J. M., Santos, V. A., & Sarubbo, L. A. (2016). Biosurfactants: Multifunctional Biomolecules of the 21st Century. International Journal of Molecular Sciences, 17(3), 401. https://doi.org/10.3390/ijms17030401
Sarangi, M. K., Padhi, S., Patel, L. D., Rath, G., Nanda, S. S., & Yi, D. K. (2022). Theranostic efficiency of biosurfactants against COVID-19 and similar viruses-A review. Journal of Drug Delivery Science and Technology, 103764. https://10.1016/j.jddst.2022.103764
Satpute, S. K., Banpurkar, A. G., Dhakephalkar, P. K., Banat, I. M., & Chopade, B. A. (2010). Methods for investigating biosurfactants and bioemulsifiers: a review. Critical reviews in biotechnology, 30(2), 127-144. https://10.3109/07388550903427280
Sen, S., Borah, S. N., Bora, A., & Deka, S. (2017). Production, characterization, and antifungal activity of a biosurfactant produced by Rhodotorula babjevae YS3. Microbial cell factories, 16(1), 1-14. https://doi.org/10.1186/s12934-017-0711-z
Sharma, D., & Singh Saharan, B. (2014). Simultaneous production of biosurfactants and bacteriocins by probiotic Lactobacillus casei MRTL3. International Journal of Microbiology, 2014, 698713. https://10.1155/2014/698713
Sharma, D., Singh, D., Sukhbir-Singh, G. M., Karamchandani, B. M., Aseri, G. K., Banat, I. M., & Satpute, S. K. (2023). Biosurfactants: Forthcomings and regulatory affairs in food-based industries. Molecules, 28(6), 2823. https://doi.org/10.3390/molecules28062823
Singh, K., Nandi, A., Sinha, A., Ghosh, A., Sengupta, S., Saha, U., ... & Verma, S. K. (2023). The paradigm of prophylactic viral outbreaks measures by microbial biosurfactants. Journal of Infection and Public Health,16(4):575-587. https://doi.org/10.1016/j.jiph.2023.02.016
Subramaniam, M. D., Venkatesan, D., Iyer, M., Subbarayan, S., Govindasami, V., Roy, A., Narayanasamy, A., Kamalakannan, S., Gopalakrishnan, A. V., Thangarasu, R., Kumar, N. S., & Vellingiri, B. (2020). Biosurfactants and anti-inflammatory activity: A potential new approach towards COVID-19. Current opinion in environmental science & health, 17, 72–81. https://doi.org/10.1016/j.coesh.2020.09.002
Thakur, S., Singh, A., Sharma, R., Aurora, R., & Jain, S. K. (2020). Biosurfactants as a novel additive in pharmaceutical formulations: current trends and future implications. Current drug metabolism, 21(11), 885-901. https://10.2174/1389200221666201008143238
Zhang, S., Liang, X., Gadd, G. M., & Zhao, Q. (2021). Marine microbial-derived antibiotics and biosurfactants as potential new agents against catheter-associated urinary tract infections. Marine Drugs, 19(5), 255. https://10.3390/md19050255
Zhen, C., Ge, X. F., Lu, Y. T., & Liu, W. Z. (2023). Chemical structure, properties and potential applications of surfactin, as well as advanced strategies for improving its microbial production. AIMS microbiology, 9(2), 195-217. https://10.3934/microbiol.2023012
Adejumo, S. A., Oli, A. N., Okoye, E. I., Nwakile, C. D., Ojiako, C. M., Okezie, U. M., Okeke, I. J., Ofomata, C. M., Attama, A. A., Okoyeh, J. N., & Esimone, C. O. (2021). Biosurfactant Production Using Mutant Strains of Pseudomonas aeruginosa and Bacillus subtilis from Agro-industrial Wastes. Advanced Pharmaceutical Bulletin, 11(3), 543–556. https://doi.org/10.34172/apb.2021.063
Adu, S. A., Naughton, P. J., Marchant, R., & Banat, I. M. (2020). Microbial biosurfactants in cosmetic and personal skincare pharmaceutical formulations. Pharmaceutics, 12(11), 1099. https://doi.org/10.3390/pharmaceutics12111099
Akbari, S., Abdurahman, N. H., Yunus, R. M., Fayaz, F., & Alara, O. R. (2018). Biosurfactants—a new frontier for social and environmental safety: a mini-review. Biotechnology Research and Innovation, 2(1),81-90. https://doi.org/10.1016/j.biori.2018.09.001
Banat, I. M., Franzetti, A., Gandolfi, I., Bestetti, G., Martinotti, M. G., Fracchia, L., Smyth, T. J., & Marchant, R. (2010). Microbial biosurfactants production, applications and future potential. Applied Microbiology and Biotechnology, 87(2), 427–444. https://doi.org/10.1007/s00253-010-2589-0
Begum, W., Saha, B., & Mandal, U. (2023). A comprehensive review on production of bio-surfactants by bio-degradation of waste carbohydrate feedstocks: an approach towards sustainable development. RSC advances, 13(36), 25599-25615. https://doi.org/10.1039/D3RA05051C
Bhadoriya, S. S., Madoriya, N., Shukla, K., & Parihar, M. S. (2013). Biosurfactants: a new pharmaceutical additive for solubility enhancement and pharmaceutical development. Biochem Pharmacol, 2(2), 113. https://doi.org/10.4172/2167-0501.1000113
Bjerk, T. R., Severino, P., Jain, S., Marques, C., Silva, A. M., Pashirova, T., & Souto, E. B. (2021). Biosurfactants: properties and applications in drug delivery, biotechnology and ecotoxicology. Bioengineering, 8(8), 115. https://doi.org/10.3390/bioengineering8080115
Campos, J. M., Stamford, T. L., Sarubbo, L. A., de Luna, J. M., Rufino, R. D., & Banat, I. M. (2013). Microbial biosurfactants as additives for food industries. Biotechnology Progress, 29(5), 1097–1108. https://doi.org/10.1002/btpr.1796
Ceresa, C., Fracchia, L., Sansotera, A. C., De Rienzo, M. A. D., & Banat, I. M. (2023). Harnessing the potential of biosurfactants for biomedical and pharmaceutical applications. Pharmaceutics, 15(8), 2156. https://doi.org/10.3390/pharmaceutics15082156
De Giani, A., Zampolli, J., & Di Gennaro, P. (2021). Recent trends on biosurfactants with antimicrobial activity produced by bacteria associated with human health: different perspectives on their properties, challenges, and potential applications. Frontiers in Microbiology, 12, 655150. https://doi.org/10.3389/fmicb.2021.655150
Dias, M. A. M., & Nitschke, M. (2023). Bacterial-derived surfactants: an update on general aspects and forthcoming applications. Brazilian Journal of Microbiology, 54(1), 103-123. https://doi.org/10.1007/s42770-023-00905-7
Dusane, D. H., Zinjarde, S. S., Venugopalan, V. P., McLean, R. J., Weber, M. M., & Rahman, P. K. (2010). Quorum sensing: implications on rhamnolipid biosurfactant production. Biotechnology & Genetic Engineering Reviews, 27, 159–184. https://doi.org/10.1080/02648725.2010.10648149
Eras-Muñoz E, Farré A, Sánchez A, Font X, Gea T. (2022) Microbial biosurfactants: a review of recent environmental applications. Bioengineered,13(5):12365-12391. https://doi.org/10.1080/21655979.2022.2074621
Flessa, S., & Huebner, C. (2021). Innovations in health care—A conceptual framework. International Journal of Environmental Research and Public Health, 18(19), 10026. https://doi.org/10.3390/ijerph181910026
Haddaji, N., Bahloul, B., Bahia, W., Bechambi, O., & Mahdhi, A. (2023). Development of nanotechnology-based drug delivery systems for controlling clinical multidrug-resistant Staphylococcus aureus and Escherichia coli Associated with Aerobic Vaginitis. Pharmaceutics, 15(8), 2133. https://doi.org/10.3390/pharmaceutics15082133
Hashim, Z. A., Maillard, J. Y., Wilson, M. J., & Waddington, R. J. (2022). Determining the potential use of biosurfactants in preventing endodontic infections. European Journal of Oral Sciences, 130(6), e12900. https://doi.org/10.1111/eos.12900
Herrmann, I. K., & Schlegel, A. A. (2022). Fostering Medical Materials Innovation. ACS Materials Au, 3(1), 24-27. https://doi.org/10.1021/acsmaterialsau.2c00054
Kaczorek, E., Pacholak, A., Zdarta, A., & Smułek, W. (2018). The impact of biosurfactants on microbial cell properties leading to hydrocarbon bioavailability increase. Colloids and Interfaces, 2(3), 35. https://doi.org/10.3390/colloids2030035
Karnwal, A., Shrivastava, S., Al-Tawaha, A. R. M. S., Kumar, G., Singh, R., Kumar, A., ... & Malik, T. (2023). Microbial Biosurfactant as an Alternate to Chemical Surfactants for Application in Cosmetics Industries in Personal and Skin Care Products: A Critical Review. BioMed Research International, 2023-2375223. https://doi.org/10.1155/2023/2375223
Khanna, A., Handa, S., Rana, S., Suttee, A., Puri, S., & Chatterjee, M. (2023). Biosurfactant from Candida: sources, classification, and emerging applications. Archives of Microbiology, 205(4), 149. https://doi.org/10.1007/s00203-023-03495-y
Kumari, K. S., Shivakrishna, P., & Ganduri, V. R. (2020). Wound healing Activities of the bioactive compounds from Micrococcus sp. OUS9 isolated from marine water. Saudi Journal of Biological Sciences, 27(9), 2398-2402. https://doi.org/10.1016/j.sjbs.2020.05.007
Ndlovu, T., Rautenbach, M., Vosloo, J. A., Khan, S., & Khan, W. (2017). Characterisation and antimicrobial activity of biosurfactant extracts produced by Bacillus amyloliquefaciens and Pseudomonas aeruginosa isolated from a wastewater treatment plant. AMB Express, 7(1), 1-19. https://doi.org/10.1186/s13568-017-0363-8
Nitschke, M., & Marangon, C. A. (2022). Microbial surfactants in nanotechnology: recent trends and applications. Critical Reviews in Biotechnology, 42(2), 294–310. https://doi.org/10.1080/07388551.2021.1933890
Ohadi, M., Forootanfar, H., Dehghannoudeh, N., Banat, I. M., & Dehghannoudeh, G. (2023). The role of surfactants and biosurfactants in the wound healing process: a review. Journal of Wound care, 32(Sup4a), xxxix–xlvi. https://doi.org/10.12968/jowc.2023.32.Sup4a.xxxix
Peele, K. A., Ch, V. R. T., & Kodali, V. P. (2016). Emulsifying activity of a biosurfactant produced by a marine bacterium. 3 Biotech, 6(2), 177. https://10.1007/s13205-016-0494-7
Perfumo, A., Rancich, I., & Banat, I. M. (2010). Possibilities and challenges for biosurfactants use in petroleum industry. Biosurfactants, 135-145.
Raza, Z. A., Shahzad, Q., Rehman, A., Taqi, M., & Ayub, A. (2022). Biosurfactants in the sustainable eradication of SARS COV-2 from the environmental surfaces. 3 Biotech, 12(10), 273. https://10.1007/s13205-022-03320-1
Ribeiro, B. G., Guerra, J. M. C., & Sarubbo, L. A. (2020). Potential food application of a biosurfactant produced by Saccharomyces cerevisiae URM 6670. Frontiers in Bioengineering and Biotechnology, 8, 434. https://doi.org/10.3389/fbioe.2020.00434
Rincón-Fontán, M., Rodríguez-López, L., Vecino, X., Cruz, J. M., & Moldes, A. B. (2020). Novel multifunctional biosurfactant obtained from corn as a stabilizing agent for antidandruff formulations based on Zn pyrithione powder. ACS omega, 5(11), 5704-5712. https://doi.org/10.1021/acsomega.9b03679
Ron, E. Z., & Rosenberg, E. (2001). Natural roles of biosurfactants. Environmental Microbiology, 3(4), 229–236. https://doi.org/10.1046/j.1462-2920.2001.00190.x
Santos, D. K., Rufino, R. D., Luna, J. M., Santos, V. A., & Sarubbo, L. A. (2016). Biosurfactants: Multifunctional Biomolecules of the 21st Century. International Journal of Molecular Sciences, 17(3), 401. https://doi.org/10.3390/ijms17030401
Sarangi, M. K., Padhi, S., Patel, L. D., Rath, G., Nanda, S. S., & Yi, D. K. (2022). Theranostic efficiency of biosurfactants against COVID-19 and similar viruses-A review. Journal of Drug Delivery Science and Technology, 103764. https://10.1016/j.jddst.2022.103764
Satpute, S. K., Banpurkar, A. G., Dhakephalkar, P. K., Banat, I. M., & Chopade, B. A. (2010). Methods for investigating biosurfactants and bioemulsifiers: a review. Critical reviews in biotechnology, 30(2), 127-144. https://10.3109/07388550903427280
Sen, S., Borah, S. N., Bora, A., & Deka, S. (2017). Production, characterization, and antifungal activity of a biosurfactant produced by Rhodotorula babjevae YS3. Microbial cell factories, 16(1), 1-14. https://doi.org/10.1186/s12934-017-0711-z
Sharma, D., & Singh Saharan, B. (2014). Simultaneous production of biosurfactants and bacteriocins by probiotic Lactobacillus casei MRTL3. International Journal of Microbiology, 2014, 698713. https://10.1155/2014/698713
Sharma, D., Singh, D., Sukhbir-Singh, G. M., Karamchandani, B. M., Aseri, G. K., Banat, I. M., & Satpute, S. K. (2023). Biosurfactants: Forthcomings and regulatory affairs in food-based industries. Molecules, 28(6), 2823. https://doi.org/10.3390/molecules28062823
Singh, K., Nandi, A., Sinha, A., Ghosh, A., Sengupta, S., Saha, U., ... & Verma, S. K. (2023). The paradigm of prophylactic viral outbreaks measures by microbial biosurfactants. Journal of Infection and Public Health,16(4):575-587. https://doi.org/10.1016/j.jiph.2023.02.016
Subramaniam, M. D., Venkatesan, D., Iyer, M., Subbarayan, S., Govindasami, V., Roy, A., Narayanasamy, A., Kamalakannan, S., Gopalakrishnan, A. V., Thangarasu, R., Kumar, N. S., & Vellingiri, B. (2020). Biosurfactants and anti-inflammatory activity: A potential new approach towards COVID-19. Current opinion in environmental science & health, 17, 72–81. https://doi.org/10.1016/j.coesh.2020.09.002
Thakur, S., Singh, A., Sharma, R., Aurora, R., & Jain, S. K. (2020). Biosurfactants as a novel additive in pharmaceutical formulations: current trends and future implications. Current drug metabolism, 21(11), 885-901. https://10.2174/1389200221666201008143238
Zhang, S., Liang, X., Gadd, G. M., & Zhao, Q. (2021). Marine microbial-derived antibiotics and biosurfactants as potential new agents against catheter-associated urinary tract infections. Marine Drugs, 19(5), 255. https://10.3390/md19050255
Zhen, C., Ge, X. F., Lu, Y. T., & Liu, W. Z. (2023). Chemical structure, properties and potential applications of surfactin, as well as advanced strategies for improving its microbial production. AIMS microbiology, 9(2), 195-217. https://10.3934/microbiol.2023012
Statistics
92 Views | 75 Downloads
How to Cite
Purohit, G., Dubey, D., Rath, S., Subhadarsini, S., Tripathi, D., Behera, S., & Sahu, L. (2024). Biosurfactants: Moving Towards Healthcare Applications. International Journal of Advancement in Life Sciences Research, 7(1), 24-37. https://doi.org/https://doi.org/10.31632/ijalsr.2024.v07i01.003
Section
Review Articles
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
.