Autism Spectrum Disorder and Gut Microbiome: A Brief Review

ASD and Gut Microbiome

  • Aindrila Banerjee Majdia Rail Bazar High School (H.S.) Majdia, Nadia, West Bengal. 741507, India.
  • Santi Ranjan Dey Department of Zoology, Rammohan College, Kolkata 700009, India. https://orcid.org/0000-0003-2769-9109
  • Indrani Basu Autism Society West Bengal, Kolkata 700032, India.
  • Mitu De Department of Botany, Gurudas College, Kolkata 700054, India. https://orcid.org/0000-0002-0757-2381

Abstract

The human microbiota consists of the 10-100 trillion symbiotic microbial cells harbored by each person, primarily bacteria in the gut. The association of the gut microbiota with human health and disease has been widely studied. A number of human disorders and diseases have been directly and indirectly associated with the microbiome. Children with Autism Spectrum Disorder (ASD) have distinctive gut microbiota compared to neurotypical children. Autism spectrum disorder (ASD) is associated with several oropharyngeal abnormalities, including dysbiosis in the oral microbiota. As there is a correlation between abnormal microbiota and development of autism like behaviour, so, modifying the gut microbiome by probiotics, prebiotics, antibiotics and fecal microbiota transplant (FMT) could be a potential route to improve GI and behavioural symptoms in children with ASD.

Keywords: Microbiome; Autism Spectrum Disorder (ASD); gut microbiota.

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How to Cite
Banerjee, A., Dey, S., Basu, I., & De, M. (2021). Autism Spectrum Disorder and Gut Microbiome: A Brief Review. International Journal of Advancement in Life Sciences Research, 4(1), 1-6. https://doi.org/https://doi.org/10.31632/ijalsr.20.v04i01.001