Periscopic View on COVID 19 Infection: A Review

Periscopic View on COVID 19 Infection

Abstract

Recently, the world has experienced an unprecedented health risk. The unknown coronavirus (SARS-CoV-2 causing COVID-19) is causing a pandemic infection as announced by World Health Organization. It emerged from Wuhan, China in December 2019 and spread worldwide. The SARS-CoV-2 originated in bats and through yet unknown intermediary animals was transmitted to humans in Wuhan. There have been around 3,935,559 reported cases of coronavirus disease 2019 (COVID-2019) and 271,170 reported deaths to date (08/05/2020). It spreads mainly through the droplet route by inhalation or contact. Incubation period 1-14 d. Asymptomatic or patients with mild symptoms is most common of the cases; case fatality nearly 2-3%). The major symptoms are fever, dry cough, fatigue and muscle pain; less common symptoms reported are runny nose, sore throat, diarrhea, chills and hemoptysis. The SARS-CoV-2 infection is a life-threatening complication of acute respiratory distress syndrome (ARDS); in severe cases with other co-morbidities, which most commonly occurs more often in elderly or immunocompromised individuals with underlying diseases. Severe expression of the infection needs treatment in the intensive care unit with indications of acute lung inflammation, ARDS, sepsis and septic shock. Diagnosis of virus in respiratory secretions is done by special molecular tests. This review presents information about history, etiology, pathogenesis, clinical diagnostics, treatment and prevention of the infection. At present, the effective antiviral drug or vaccine is not yet available and the number of infections/death tolls surging day by day, so updated knowledge of this infection is always needed prevention for fighting the virus.

Keywords: Coronaviruses, COVID-19, SARS-CoV-2, acute respiratory distress syndrome (ARDS), SIRS.

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Ansar, W. (2020). Periscopic View on COVID 19 Infection: A Review. International Journal of Advancement in Life Sciences Research, 3(3), 1-15. Retrieved from http://ijalsr.org/index.php/journal/article/view/105
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